Toxic epidermal necrolysis in a patient with severe aplastic anemia treated with cyclosporin A and G-CSF
- PMID: 11321886
Toxic epidermal necrolysis in a patient with severe aplastic anemia treated with cyclosporin A and G-CSF
Abstract
Toxic epidermal necrolysis (TEN) and severe aplastic anemia (SAA) are rare nonpredictable side effects of several drugs. To our knowledge there are no reports on the coexistence of these two disorders. This study presents a 23 year-old man with TEN diagnosed 6 days after treatment with aminophenazone, paracetamol and phenoxymethylpenicillin. The resolution of the skin disorder was observed after few days of treatment with G-CSF and cyclosporin A. In contrast, SAA only partially responded to treatment with these agents.
Similar articles
-
Toxic epidermal necrolysis treated with cyclosporin and granulocyte colony stimulating factor.Clin Exp Dermatol. 1997 May;22(3):146-7. Clin Exp Dermatol. 1997. PMID: 9425696
-
Treatment of severe aplastic anemia with antilymphocyte globulin, cyclosporine and two different granulocyte colony-stimulating factor regimens: a GITMO prospective randomized study.Haematologica. 2004 Sep;89(9):1054-61. Haematologica. 2004. PMID: 15377466 Clinical Trial.
-
Granulocyte colony-stimulating factor in toxic epidermal necrolysis (TEN) and Chelsea & Westminster TEN management protocol [corrected].Br J Dermatol. 2010 Apr;162(4):860-5. doi: 10.1111/j.1365-2133.2009.09585.x. Epub 2009 Nov 11. Br J Dermatol. 2010. PMID: 19912214
-
Cyclosporine for SJS/TEN: a case series and review of the literature.Cutis. 2011 Jan;87(1):24-9. Cutis. 2011. PMID: 21323097 Review.
-
Prospective, noncomparative open study from Kuwait of the role of intravenous immunoglobulin in the treatment of toxic epidermal necrolysis.Int J Dermatol. 2004 Nov;43(11):847-51. doi: 10.1111/j.1365-4632.2004.02048.x. Int J Dermatol. 2004. PMID: 15533072 Review.
Cited by
-
Toxic epidermal necrolysis and Stevens-Johnson syndrome.Orphanet J Rare Dis. 2010 Dec 16;5:39. doi: 10.1186/1750-1172-5-39. Orphanet J Rare Dis. 2010. PMID: 21162721 Free PMC article. Review.
-
Systemic interventions for treatment of Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome.Cochrane Database Syst Rev. 2022 Mar 11;3(3):CD013130. doi: 10.1002/14651858.CD013130.pub2. Cochrane Database Syst Rev. 2022. PMID: 35274741 Free PMC article.
-
The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China.J Immunol Res. 2018 Feb 11;2018:4320195. doi: 10.1155/2018/4320195. eCollection 2018. J Immunol Res. 2018. PMID: 29607330 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical