Comment on

• Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells.

  Kaech SM, Ahmed R. Kaech SM, et al. Nat Immunol. 2001 May;2(5):415-22. doi: 10.1038/87720. Nat Immunol. 2001. PMID: 11323695 Free PMC article.
• Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation.

  van Stipdonk MJ, Lemmens EE, Schoenberger SP. van Stipdonk MJ, et al. Nat Immunol. 2001 May;2(5):423-9. doi: 10.1038/87730. Nat Immunol. 2001. PMID: 11323696