Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Apr;34(4):204-6.

[Expression of integrin beta 3 and intracellular adhesion molecule in endometrium and endometriotic tissue]

[Article in Chinese]
J Wu  1 , J Zhang, Y Liu
Affiliations
  • PMID: 11326914

[Expression of integrin beta 3 and intracellular adhesion molecule in endometrium and endometriotic tissue]

[Article in Chinese]
J Wu et al. Zhonghua Fu Chan Ke Za Zhi. 1999 Apr.

Abstract

Objective: To study the relationship between integrin beta 3, intracellular adhesion molecule (ICAM) and endometriosis.

Methods: The expression of integrin beta 3 and ICAM protein were determined in 3 batches by immunoblotting method in 15 endometrium and 15 endometriotic tissues of patients with endometriosis and 30 endometrium from non-endometriosis subjects during the same menstrual phase. The results were scanned and semi-quantified, and then analysed by F test and t test.

Results: The results from 3 measurements showed the same trend. Endometrium from patients with endometriosis expressed significantly fewer integrin beta 3 and ICAM protein than those without endometriosis. On the other hand, the expression of integrin beta 3 in endometriotic tissue was significantly lower while the ICAM expression was significantly higher than those in controls.

Conclusions: In patients with endometriosis, integrin beta 3 and ICAM expression changed significantly from eutopic to ectopic endometrium which may be related to the development of endometriosis and infertility.

PubMed Disclaimer

Publication types