Coronary artery disease: part 2. Treatment
- PMID: 11342512
- PMCID: PMC1071391
- DOI: 10.1136/ewjm.174.5.330
Coronary artery disease: part 2. Treatment
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- UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet1998;352: 837-853 [erratum published in Lancet 1999;354:602]. Intensive treatment of type 2 diabetes reduced the risk of MI by a nonsignificant 16% (attributable risk reduction [ARR]=3/1,000 patient-years; P > 0.05). - PubMed
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- Caprie Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet1996;348: 1329-1339. Clopidogrel reduced the combined incidence of ischemic stroke, MI, or vascular death from 5.8% to 5.3% (relative risk [RR]=9%, ARR=0.5%). Because of its expense, clopidogrel is not considered a first-line agent for the treatment of stable angina. - PubMed
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