The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation
- PMID: 11343911
- DOI: 10.1016/s0968-0004(01)01787-x
The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation
Abstract
Sequence profile analysis was used to detect a conserved globular domain in several proteins including deltex, Trip12 and poly-ADP-ribose polymerase homologs. It was named the WWE domain after its most conserved residues and is predicted to mediate specific protein-protein interactions in ubiquitin and ADP-ribose conjugation systems.
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