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. 1974 Feb;53(2):559-64.
doi: 10.1172/JCI107590.

Activation of human blood monocytes by products of sensitized lymphocytes

R E Rocklin  1 , C T Winston, J R David
Affiliations

Activation of human blood monocytes by products of sensitized lymphocytes

R E Rocklin et al. J Clin Invest. 1974 Feb.

Abstract

Studies were carried out to determine whether products of activated human lymphocytes altered human monocyte function. Supernatants from sensitized human lymphocytes stimulated by specific antigen were cultured with monolayers of human monocytes. Such monocytes exhibited enhanced adherence to their culture vessels and increased glucose carbon-1 oxidation after 2-3 days of incubation. The substance responsible for these effects was found to elute from Sephadex G-100 gel columns in a fraction with 23,000 mol wt, the same fraction containing human migration inhibitory factor.

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References

    1. J Exp Med. 1971 Jun 1;133(6):1356-76 - PubMed
    1. Cell Immunol. 1972 Dec;5(4):536-43 - PubMed
    1. J Exp Med. 1973 Feb 1;137(2):275-90 - PubMed
    1. J Biol Chem. 1951 Nov;193(1):265-75 - PubMed
    1. J Biol Chem. 1958 Jul;233(1):184-8 - PubMed

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