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Comment
. 2001 May 11;292(5519):1151-3.
doi: 10.1126/science.1060011.

African origin of modern humans in East Asia: a tale of 12,000 Y chromosomes

Y Ke  1 , B Su, X Song, D Lu, L Chen, H Li, C Qi, S Marzuki, R Deka, P Underhill, C Xiao, M Shriver, J Lell, D Wallace, R S Wells, M Seielstad, P Oefner, D Zhu, J Jin, W Huang, R Chakraborty, Z Chen, L Jin
Affiliations
Comment

African origin of modern humans in East Asia: a tale of 12,000 Y chromosomes

Y Ke et al. Science. .

Abstract

To test the hypotheses of modern human origin in East Asia, we sampled 12,127 male individuals from 163 populations and typed for three Y chromosome biallelic markers (YAP, M89, and M130). All the individuals carried a mutation at one of the three sites. These three mutations (YAP+, M89T, and M130T) coalesce to another mutation (M168T), which originated in Africa about 35,000 to 89,000 years ago. Therefore, the data do not support even a minimal in situ hominid contribution in the origin of anatomically modern humans in East Asia.

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