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Review
. 2001 Apr:26 Suppl 1:42-5.
doi: 10.1007/pl00014031.

[GPIIb/IIIa blockers for optimizing thrombolysis in acute myocardial infarct]

[Article in German]
T K Nordt  1 , K Peter, C Bode
Affiliations
Review

[GPIIb/IIIa blockers for optimizing thrombolysis in acute myocardial infarct]

[Article in German]
T K Nordt et al. Herz. 2001 Apr.

Abstract

Thrombolytic therapy is an established strategy for the treatment of acute myocardial infarction. GPIIB/IIIA BLOCKERS + MODERN THROMBOLYTIC AGENTS: At present, the most attractive development for optimizing thrombolytic therapy includes the use of GPIIb/IIIa blockers in combination with modern thrombolytic agents such as alteplase and reteplase. The review summarizes the available results of clinical studies using standard doses of thrombolytic agents (TAMI 8, IMPACT-AMI, and PARADIGM) or reduced dosages of thrombolytic agents (TIMI 14 and SPEED) for combination therapy. The review also focuses on the implications of the combination therapy for coronary angioplasty immediately following coronary thrombolysis.

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