Case Reports
doi: 10.1016/s0924-9338(01)00562-4.
Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: a case-series
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- PMID: 11353598
- DOI: 10.1016/s0924-9338(01)00562-4
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Case Reports
Long-term effects of topiramate on bipolar mood instability, weight change and glycemic control: a case-series
Eur Psychiatry.
2001 Apr.
Abstract
Topiramate is an antiepileptic agent, which is being investigated as a mood-stabilizer. Three obese individuals with DSM-IV bipolar I disorder and type II diabetes mellitus received topiramate treatment in combination with antipsychotics and valproate or carbamazepine. In addition to improved mood stability, these individuals lost between 16 to 20.5% of their pre-topiramate body weight and also achieved significant glycemic control.
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