Comparative in vitro activities of gemifloxacin, other quinolones, and nonquinolone antimicrobials against obligately anaerobic bacteria
- PMID: 11353648
- PMCID: PMC90568
- DOI: 10.1128/AAC.45.6.1896-1899.2001
Comparative in vitro activities of gemifloxacin, other quinolones, and nonquinolone antimicrobials against obligately anaerobic bacteria
Abstract
The in vitro activity of gemifloxacin was compared to that of other quinolone and nonquinolone antimicrobials against 204 anaerobes by the agar dilution technique. The data indicate that gemifloxacin has a rather selective anaerobic activity. Most Peptostreptococcus, Porphyromonas, and Fusobacterium species are susceptible, while gemifloxacin's activity against other gram-negative anaerobes appears to be variable.
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References
-
- Claros M C, Citron D M, Hunt-Gerardo S, Goldstein E J, Schönian G, Montag T, Hampel B, Rodloff A C. Characterization of indole-negative Bacteroides fragilis group species with use of polymerase chain reaction fingerprinting and resistance profiles. Clin Infect Dis. 1996;23(Suppl. 1):S66–S72. - PubMed
-
- Claros M C, Papke Y, Kleinkauf N, Adler D, Citron D M, Hunt-Gerardo S, Montag T, Goldstein E J C, Rodloff A C. Characteristics of Fusobacterium ulcerans, a new and unusual species compared with Fusobacterium varium and Fusobacterium mortiferum. Anaerobe. 1999;5:137–140.
-
- Dubois J, St-Pierre C. Comparative in vitro activity and post-antibiotic effect of gemifloxacin against Legionella spp. J Antimicrob Chemother. 2000;45(Suppl.1):41–46. - PubMed
-
- Fuchs P C, Barry A L, Brown S D. In vitro activity of gemifloxacin against contemporary clinical bacterial isolates from eleven North American medical centers, and assessment of disk diffusion test interpretive criteria. Diagn Microbiol Infect Dis. 2000;38:243–253. - PubMed
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