In vitro activities of ertapenem (MK-0826) against clinical bacterial isolates from 11 North American medical centers
- PMID: 11353653
- PMCID: PMC90573
- DOI: 10.1128/AAC.45.6.1915-1918.2001
In vitro activities of ertapenem (MK-0826) against clinical bacterial isolates from 11 North American medical centers
Abstract
This study compared the in vitro activities of the new long-half-life carbapenem ertapenem (also known as MK-0826 and L-749,345) with those of imipenem, amoxicillin-clavulanate, and ciprofloxacin against 5,558 recent clinical isolates from 11 North American medical centers. We confirmed the greater activity of ertapenem than of imipenem against the Enterobacteriaceae and the greater activity of imipenem against pseudomonads and gram-positive bacteria.
References
-
- Fuchs P C, Barry A L, Brown S D. In-vitro antimicrobial activity of a carbapenem, MK-0826 (L-749,345) and provisional interpretive criteria for disc tests. J Antimicrob Chemother. 1999;43:703–706. - PubMed
-
- Kohler J, Dorso K L, Young K, Hammond G G, Rosen H, Kropp H, Silver L L. In vitro activities of the potent, broad-spectrum carbapenem MK-0826 (L-749,345) against broad-spectrum β-lactamase- and extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli clinical isolates. Antimicrob Agents Chemother. 1999;43:1170–1176. - PMC - PubMed
-
- National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 4th ed. Approved standard M7–A4. Wayne, Pa: National Committee for Clinical Laboratory Standards; 1997.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
