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. 1995 Oct;1(9):29-30.

Can the conundrums of ACTG 175 be solved? An interview with Martin S. Hirsch, MD

  • PMID: 11362965

Can the conundrums of ACTG 175 be solved? An interview with Martin S. Hirsch, MD

M S Hirsch. J Int Assoc Physicians AIDS Care. 1995 Oct.

Abstract

AIDS: An interview with Martin S. Hirsch, planner of ACTG 175, is presented. Dr. Hirsch provides his thoughts on whether ddI monotherapy is as good as two-drug therapy; why the increase in CD4 cell counts with AZT monotherapy in treatment-naive people was less than what has been seen in other trials; whether big clinical end-point trails, like ACTG 175, can continue to be done; and whether the dropouts were consistent across arms in this trial.

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