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. 1996 Aug 2:(no 252):5.

3TC: combination trial stopped early as clinical benefit shown

J S James
  • PMID: 11363752

3TC: combination trial stopped early as clinical benefit shown

J S James. AIDS Treat News. .

Abstract

AIDS: The DSMB (data safety monitoring board) stopped a major trial of 3TC (lamivudine) when the ongoing study showed a significant reduction in the rates of death or disease progression when 3TC was added to other antiretroviral regimens. The trial was discontinued by unanimous consent. A separate pediatric trial is now underway, monitoring the effects of 3TC in delaying disease progression or death in children.

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