DNA and other technologies for HIV vaccines
- PMID: 11365275
DNA and other technologies for HIV vaccines
Abstract
AIDS: DNA-based vaccines may hold the key to controlling the spread of infectious diseases, including HIV. New technologies have made it possible to isolate and clone stretches of the DNA strand that contain instructions for producing molecules useful in immunizations. There are five technologies for making vaccines: live attenuated (weakened) vaccines, killed whole viruses, purified component vaccines (not used to make HIV vaccines), genetically engineered vaccines, and DNA vaccines. Current efforts to harness each method to produce an effective vaccine, early successes with DNA vaccines, and the preliminary results of two current vaccine candidate studies are described. An extensive bibliography and Internet addresses for several online resources covering HIV vaccine development are provided.
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