Abstract

AIDS: The 12th World AIDS Conference in Geneva explored issues associated with the use of antiretrovirals and resistance. Areas examined included resistance to new antiretroviral agents, the use of Hydroxyurea as a standard therapy, novel dosing strategies, new antiretroviral agents, and dual protease inhibitor therapy. Major conference themes involving antiretroviral resistance examined resistance profiles of new antiretroviral agents, cross-resistance within and across drug classes, the use of genotype and phenotype analysis, and the transmission of multi-drug resistant virus. While information on salvage therapy remains disappointing, it is noted that several ongoing trials are continuing to address the issue.