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. 1998 Dec;10(10):4-5.

Macrophages--promise and peril

[Article in English, French]
No authors listed
  • PMID: 11366018

Macrophages--promise and peril

[Article in English, French]
No authors listed. TreatmentUpdate. 1998 Dec.

Abstract

AIDS: Anti-HIV agents can suppress virus levels in blood and lymph nodes by inhibiting HIV from making infected T-cells into virus producers. However, anti-HIV agents are not as effective in suppressing viral replication in cells that are known as macrophages (macs). HIV-infected macs do not die as quickly as infected T-cells, and as macs move through the body, they spread HIV. Macs can hide in places that tend to resist anti-HIV drug penetration, such as the eyes or the brain. AOP-RANTES is one of the few drugs that can block the infection of macs.

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