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. 1999 Jan;13(1):4-5.

Abacavir for salvage or intensification

G Torres
  • PMID: 11366111

Abacavir for salvage or intensification

G Torres. GMHC Treat Issues. 1999 Jan.

Abstract

AIDS: Abacavir (Ziagen), a newly approved nucleoside analog, could be one of the most potent antiretrovirals available. Most of the clinical trials on abacavir have focused on patients who have never been treated for HIV, and they have responded well to the drug. The drug is not expected to be as effective in patients who have exhausted treatment options, as was demonstrated by Glaxo study CNA2007. The most common side effect of abacavir was skin rash. Some participants also reported systemic flu-like symptoms. Abacavir shows promise in intensification therapies where a drug is added to an established regimen that is not working, and in salvage therapies where patients have few treatment options remaining.

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