Can a $4 drug stop vertical HIV transmission?
- PMID: 11366985
Can a $4 drug stop vertical HIV transmission?
Abstract
AIDS: Researchers have determined that a $4 dose of Nevirapine, which is 70 times cheaper than a short course of AZT therapy, is more effective than the AZT treatment in reducing the transmission of HIV from mother to baby. About 1,800 infants are born each day with HIV infection, and an estimated 45 percent of pregnant women in South Africa will be infected by the end of the year. The Nevirapine therapy still remains too expensive for much of the world, and there are still many women who are not tested during pregnancy and do not know they are at risk of transmitting the disease. Because of the stigma, many African women decline testing even when it is free and treatment is available. A study in Uganda found that Nevirapine lowers the risk of HIV transmission by breast feeding by nearly 50 percent during a baby's first four months. Vertical transmission remains a difficult issue, especially where contaminated water supplies could put an infant at risk for other infections when they are fed formula mixed with contaminated water.
Similar articles
-
Perinatal transmission.AIDS Policy Law. 1999 Aug 6;14(14):12. AIDS Policy Law. 1999. PMID: 11367002
-
Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach.PLoS Med. 2007 Aug;4(8):e257. doi: 10.1371/journal.pmed.0040257. PLoS Med. 2007. PMID: 17713983 Free PMC article.
-
Cost-effectiveness of interventions to reduce vertical HIV transmission from pregnant women who have not received prenatal care.Med Decis Making. 2004 Jan-Feb;24(1):30-9. doi: 10.1177/0272989X03261570. Med Decis Making. 2004. PMID: 15005952
-
International recommendations on antiretroviral drugs for treatment of HIV-infected women and prevention of mother-to-child HIV transmission in resource-limited settings: 2006 update.Am J Obstet Gynecol. 2007 Sep;197(3 Suppl):S42-55. doi: 10.1016/j.ajog.2007.03.001. Am J Obstet Gynecol. 2007. PMID: 17825650 Review.
-
Prevention of mother-to-child transmission of HIV in Africa.Top HIV Med. 2004 Dec-2005 Jan;12(5):130-4. Top HIV Med. 2004. PMID: 15647608 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical