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Review
. 2001 May 1;11(9):R356-60.
doi: 10.1016/s0960-9822(01)00193-2.

Human disease: calcium signaling in polycystic kidney disease

S Somlo  1 , B Ehrlich
Affiliations
Free article
Review

Human disease: calcium signaling in polycystic kidney disease

S Somlo et al. Curr Biol. .
Free article

Abstract

Polycystic kidney disease results from loss of function of either of two novel proteins, polycystin-1 or polycystin-2. Recent studies show that intracellular calcium signaling is important in kidney development, and define defects in this signaling pathway as the basis of cyst formation in polycystic kidney disease.

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