Improved acetylating radioenzymatic assay of amikacin, tobramycin, and sisomicin in serum
- PMID: 1137391
- PMCID: PMC429141
- DOI: 10.1128/AAC.7.3.374
Improved acetylating radioenzymatic assay of amikacin, tobramycin, and sisomicin in serum
Abstract
The acetylating radioenzymatic assay of aminoglycosides was modified by using [(3)H]acetyl coenzyme A as cosubstrate. This modification reduces the cost of the method by at least one-half without sacrificing rapidity or accuracy.
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