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. 2001 Jun;39(6):2294-7.
doi: 10.1128/JCM.39.6.2294-2297.2001.

Biofilm formation by gram-negative bacteria on central venous catheter connectors: effect of conditioning films in a laboratory model

R Murga  1 , J M Miller, R M Donlan
Affiliations

Biofilm formation by gram-negative bacteria on central venous catheter connectors: effect of conditioning films in a laboratory model

R Murga et al. J Clin Microbiol. 2001 Jun.

Abstract

Human blood components have been shown to enhance biofilm formation by gram-positive bacteria. We investigated the effect of human blood on biofilm formation on the inner lumen of needleless central venous catheter connectors by several gram-negative bacteria, specifically Enterobacter cloacae, Pseudomonas aeruginosa, and Pantoea agglomerans. Results suggest that a conditioning film of blood components promotes biofilm formation by these organisms in an in vitro system.

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Figures

FIG. 1
FIG. 1
Diagram of biofilm receptor setup.
FIG. 2
FIG. 2
E. cloacae biofilm formation on NCs as a function of preconditioning.
FIG. 3
FIG. 3
P. aeruginosa biofilm formation on NCs as a function of preconditioning.
FIG. 4
FIG. 4
P. agglomerans biofilm formation on NCs as a function of preconditioning.
See this image and copyright information in PMC

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