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. 2001 Jun;39(6):2348-50.
doi: 10.1128/JCM.39.6.2348-2350.2001.

Antifungal susceptibilities, varieties, and electrophoretic karyotypes of clinical isolates of Cryptococcus neoformans from Brazil, Chile, and Venezuela

B M Calvo  1 , A L Colombo, O Fischman, A Santiago, L Thompson, M Lazera, F Telles, K Fukushima, K Nishimura, R Tanaka, M Myiajy, M L Moretti-Branchini
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Antifungal susceptibilities, varieties, and electrophoretic karyotypes of clinical isolates of Cryptococcus neoformans from Brazil, Chile, and Venezuela

B M Calvo et al. J Clin Microbiol. 2001 Jun.

Abstract

One hundred clinical isolates of Cryptococcus neoformans from human immunodeficiency virus (HIV)-infected and non-HIV-infected patients from Brazil, Chile, and Venezuela were separated according to varieties and tested for antifungal susceptibility. A high susceptibility to antifungal agents was observed among all the isolates. The electrophoretic karyotyping of 51 strains revealed good discrimination among Cryptococcus neoformans var. neoformans strains.

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Figures

FIG. 1
FIG. 1
EK profiles of C. neoformans var. gattii and C. neoformans var. neoformans. The serotypes are indicated above the lanes. PM, molecular size; Sc, S. cerevisiae DNA marker.
FIG. 2
FIG. 2
Dendrogram corresponding to Fig. 1. The values were generated from the Dice coefficients and illustrate the relatedness of varieties and serotypes of C. neoformans var. neoformans and C. neoformans var. gattii isolates. Numbers 2, 3, and 4 represent C. neoformans var. gattii serotypes B, C, and C, respectively. Numbers 7, 8, 9, 10, and 11 represent C. neoformans var. neoformans serotypes AD, AD, A, D, and A, respectively. Values at the top are percent similarity.
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