Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001 Jun;22(6):322-7.
doi: 10.1016/s1471-4906(01)01938-x.

The amplification of TCR signaling by dynamic membrane microdomains

A Viola  1
Affiliations
Review

The amplification of TCR signaling by dynamic membrane microdomains

A Viola. Trends Immunol. 2001 Jun.

Abstract

Modulation of T-cell receptor (TCR) signaling is essential for the regulation of T-cell responses to infectious agents. Recently, many laboratories have suggested that TCR triggering might be compartmentalized in plasma membrane microdomains called rafts. Results on the role of lipid rafts as signaling units in TCR triggering suggest that rafts might be used by T cells to fine-tune their immune responsiveness.

PubMed Disclaimer

Comment in

LinkOut - more resources