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. 1975 Jun 14;112(13 Spec No):89-90.

Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis

E Whitehead

Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis

E Whitehead. Can Med Assoc J. .

Abstract

The combination trimethoprim-sulfamethoxazole was given in high dosage (four tablets twice daily) for either 2 or 5 days to 20 patients with sinusitis diagnosed on clinical grounds. In 11 the infection was improved or cured. Swabs cultured from 18 patients of the series produced no growth in 8. The organisms most likely to be isolated are Hemophilus influenzae and Diplococcus pneumoniae.

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References

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