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. 1975 Apr;2(4):459-67.
doi: 10.1093/nar/2.4.459.

A proton magnetic resonance investigation of the glycosyl torsion angle of uracil nucleosides and nucleotides

T Schleich, T R Lusebrink, B P Cross, N P Johnson
Free PMC article

A proton magnetic resonance investigation of the glycosyl torsion angle of uracil nucleosides and nucleotides

T Schleich et al. Nucleic Acids Res. 1975 Apr.
Free PMC article

Abstract

The use of line-shape decomposition techniques permitted the small 5-bond (5-J51') and 4-bond (4-J61') proton-proton coupling constants of a series of uracil nucleosides and nucleotides to be determined accurately. From an analysis of these coupling constants we have determined that the uracil base is in a predominantly anti conformation in aqueous solution and the mean position is not substantially altered by phosphate substitution at the 2', 3', or 5' positions, by changing the furanose stereochemistry from a ribose to a deoxyribose or an arabinose, or by an increase in temperature of 43 degree C.

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References

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