Review
The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis
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- PMID: 11382593
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Review
The role of matrix metalloproteinases in tumor invasion, metastasis, and angiogenesis
Surg Oncol Clin N Am.
2001 Apr.
Abstract
Tumor invasion and metastasis formation are the hallmarks of malignant cancer. Metastatic spread of cancer cells is a result of a complex cascade of cellular events. This article discusses the matrix metalloproteinase family, the regulation of matrix metalloproteinase activity, and the functions of matrix metalloproteinases in tumor progression.
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