Case Reports
Diazepam poisoning with one-month monitoring of diazepam and nordiazepam blood levels
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- PMID: 11383664
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Case Reports
Diazepam poisoning with one-month monitoring of diazepam and nordiazepam blood levels
Vet Hum Toxicol.
2001 Jun.
Abstract
A 54-y-old man ingested 2 g of bulk laboratory diazepam and was treated with activated charcoal, enhanced diuresis and flumazenil infusion. The treatment resulted in awakening, but the patient had drowsiness, dysarthria, diplopia, and dizziness for 9 d. Blood levels of diazepam and its main metabolite, nordiazepam, were obtained for 1 mo. The half-lives in this benzodiazepine overdose were longer than those seen with therapeutic doses. Benzodiazepines should not be readministrated when patients awake after suicide attempts.
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