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. 2001 May-Jun;21(3):219-30.
doi: 10.1177/0272989X0102100307.

Bayesian assessment of sample size for clinical trials of cost-effectiveness

A O'Hagan  1 , J W Stevens
Affiliations

Bayesian assessment of sample size for clinical trials of cost-effectiveness

A O'Hagan et al. Med Decis Making. 2001 May-Jun.

Abstract

The authors present an analysis of the choice of sample sizes for demonstrating cost-effectiveness of a new treatment or procedure, when data on both cost and efficacy will be collected in a clinical trial. The Bayesian approach to statistics is employed, as well as a novel Bayesian criterion that provides insight into the sample size problem and offers a very flexible formulation.

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