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Review
. 2001 Jun;94(6):265-9.
doi: 10.1177/014107680109400603.

Water retention and aquaporins in heart failure, liver disease and pregnancy

R W Schrier  1 , M A Cadnapaphornchai, M Ohara
Affiliations
Review

Water retention and aquaporins in heart failure, liver disease and pregnancy

R W Schrier et al. J R Soc Med. 2001 Jun.
No abstract available

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Figures

Figure 1
Figure 1
Backward and forward theories of heart failure [Modified by permission, from Peters JP, Am J Med 1952;12:66]
Figure 2
Figure 2
Underfill and overfill hypotheses of oedema formation in cirrhosis [Modified by permission, from Schrier RW, J R Coll Physicians 1992;26:295]
Figure 3
Figure 3
Underfill and overfill hypotheses of oedema formation in pregnancy
Figure 4
Figure 4
Sequence of events in which a decrease in cardiac output initiates water retention [Modified by permission, from Schrier RW, Ann Intern Med 1990;113:155]
Figure 5
Figure 5
Sequence of events in which peripheral arterial vasodilation initiates water retention [Modified by permission, from Schrier RW, J Am Soc Nephrol 1992;2:1549]
Figure 6
Figure 6
Effect of VPA-985 administration on urinary AQP2 excretion of heart failure patients according to dose groups. (X axis represents the collection periods. Day - 1 is the baseline observation and day + 1 is the study period. ▪ Baseline; ○ Placebo; • 30 mg; ▵ 75 mg; □ 150 mg; ♦ 250 mg) [Reprinted by permission, from Ref. 20]
See this image and copyright information in PMC

References

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    1. Arroyo V, Rodes J, Gutierrez-Lizarraga MA, Revert L. Prognostic value of spontaneous hyponatremia in cirrhosis with ascites. Am J Dig Dis 1976;21: 249-56 - PubMed
    1. Starling EH. On the absorption of fluid from the connective tissue spaces. J Physiol (Lond) 1896;19: 312 - PMC - PubMed
    1. Hope JA. A Treatise on the Diseases of the Heart and Blood Vessels. London: William Kid, 1832
    1. Mackenzie J. Disease of the Heart, (3rd edn). London: Oxford University Press, 1913