Review
doi: 10.1038/35073057.
The junction-resolving enzymes
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- PMID: 11389467
- DOI: 10.1038/35073057
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Review
The junction-resolving enzymes
Nat Rev Mol Cell Biol.
2001 Jun.
Abstract
Junction-resolving enzymes are ubiquitous nucleases that are important for DNA repair and recombination and act on DNA molecules containing branch points, especially four-way junctions. They show a pronounced selectivity for the structure of the DNA substrate but, despite its importance, the structural selectivity is not well understood. This poses an intriguing challenge in molecular recognition on a relatively large scale.
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