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. 2001 Jun 4;193(11):F41-6.
doi: 10.1084/jem.193.11.f41.

Certified professionals: CD4(+)CD25(+) suppressor T cells

E M Shevach  1
Affiliations

Certified professionals: CD4(+)CD25(+) suppressor T cells

E M Shevach. J Exp Med. .
No abstract available

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References

    1. Sakaguchi S., Sakaguchi N., Asano M., Itoh M., Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995;160:1151–1164. - PubMed
    1. Asano M., Toda M., Sakaguchi N., Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 1996;184:387–396. - PMC - PubMed
    1. Suri-Payer E., Amar A.Z., Thornton A.M., Shevach E.M. CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 1998;160:1212–1218. - PubMed
    1. Thornton A.M., Shevach E.M. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 1998;188:287–296. - PMC - PubMed
    1. Read S., Mauze S., Asseman C., Bean A., Coffman R., Powrie F. CD38CD45RBlow T cellsa population of T cells with immune regulatory activities in vitro. Eur. J. Immunol. 1998;28:3435–3447. - PubMed

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