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. 1998 Oct:13:231-240.
doi: 10.1152/physiologyonline.1998.13.5.231.

Proteinase-Activated Receptors: New Functions for Old Enzymes

Stephan K. Böhm  1 , Karen McConalogue, Wuyi Kong, Nigel W. Bunnett
Affiliations

Proteinase-Activated Receptors: New Functions for Old Enzymes

Stephan K. Böhm et al. News Physiol Sci. 1998 Oct.

Abstract

Although proteases are traditionally viewed as degradative enzymes, characterization of a family of G protein-coupled receptors that are activated by proteolysis reveals a new role. Certain proteases function as signaling molecules that specifically regulate cells by cleaving and activating a family of proteinase-activated receptors.

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