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. 1999 Apr:14:80-84.
doi: 10.1152/physiologyonline.1999.14.2.80.

Renal Transport of Urate in Humans

Françoise Roch-Ramel  1 , Barbara Guisan
Affiliations

Renal Transport of Urate in Humans

Françoise Roch-Ramel et al. News Physiol Sci. 1999 Apr.

Abstract

The theory of the "four-component model" of urate excretion in humans is reevaluated, considering that a decrease in urate excretion induced by drugs like pyrazinamide or by endogenous compounds like lactate and ketone bodies might be a result of stimulation of urate reabsorption and not, as previously considered, of inhibition of urate secretion.

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