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. 2000 Apr:15:83-89.
doi: 10.1152/physiologyonline.2000.15.2.83.

The Time Course of Signaling at Central Glutamatergic Synapses

Affiliations

The Time Course of Signaling at Central Glutamatergic Synapses

Peter Jonas. News Physiol Sci. 2000 Apr.

Abstract

Glutamate is the main excitatory transmitter in the mammalian CNS, mediating fast synaptic transmission primarily by activation of AMPA-type glutamate receptor channels. Both synaptic structure and a cell-specific molecular switch in the AMPA receptor subunit expression are involved in the regulation of the synaptic signaling time course.

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