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. 2000 Dec:15:319-325.
doi: 10.1152/physiologyonline.2000.15.6.319.

Toward an Integrative Concept of Control of Total Body Sodium

Affiliations

Toward an Integrative Concept of Control of Total Body Sodium

H. Wolfgang Reinhardt et al. News Physiol Sci. 2000 Dec.

Abstract

Total body sodium (TBSodium) is a major determinant of body water and arterial pressure. Several observations, in particular that of a "sodium memory," indicate that TBSodium is a controlled variable. Various regulatory elements are involved, e.g., the renin-angiotensin-aldosterone system, atrial receptors, and renal arterial pressure. Balance studies in dogs provide new insights into their contributions to TBSodium control.

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