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Review
. 2001 Feb:16:23-8.
doi: 10.1152/physiologyonline.2001.16.1.23.

Gastroduodenal mucosal alkaline secretion and mucosal protection

G Flemström  1 , J I Isenberg
Affiliations
Review

Gastroduodenal mucosal alkaline secretion and mucosal protection

G Flemström et al. News Physiol Sci. 2001 Feb.

Abstract

The gastroduodenal mucosa is a dynamic barrier restricting entry of gastric acid and other potentially hostile luminal contents. Mucosal HCO3(-) is a key element in preventing epithelial damage, and knowledge about HCO3(-) transport processes, including the role of the cystic fibrosis transmembrane conductance regulator channel, and their neurohumoral control are in rapid progress.

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