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Comparative Study
. 1975 Jul;22(4):486-94.
doi: 10.1007/BF03004864.

Response to hypercapnia under ketamine anaesthesia

M G Soliman, G F Brindle, G Kuster
Comparative Study

Response to hypercapnia under ketamine anaesthesia

M G Soliman et al. Can Anaesth Soc J. 1975 Jul.

Abstract

The respiratory response to hypercapnia in dogs anaesthetized with ketamine was increased. This respiratory stimulation was most probably due to a direct effect of the drug on the medullary respiratory neurones. This effect was not modified by preanaesthetic medication pentobarbitone 5 mg/kg or morphine 0.1 mg/kg. Catecholamine response to hypercapnia was essentially the same as that reported by hypercapnic dogs anaesthetized with thiopentone.

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References

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