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Case Reports
. 2001 May;28(5):271-5.
doi: 10.1034/j.1600-0560.2001.028005271.x.

Olmsted syndrome

Affiliations
Case Reports

Olmsted syndrome

E Fonseca et al. J Cutan Pathol. 2001 May.

Abstract

Olmsted syndrome is an uncommon inherited disorder of keratinization that presents mutilating palmoplantar keratoderma, perioral hyperkeratosis, leukokeratosis and alopecia. We report a case of this rare syndrome diagnosed in a 48-year-old woman and confirms the existence of a generalized abnormality in keratin expression. Immunoreactivity in our case suggests an abnormal expression of keratins 5 and 14 similar to the observed in other hyperproliferative disorders.

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