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. 2001 May;40(4):909-16.
doi: 10.1046/j.1365-2958.2001.02434.x.

Transcription of essential cell division genes is linked to chromosome replication in Escherichia coli

G Liu  1 , K Begg, A Geddes, W D Donachie
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Free article

Transcription of essential cell division genes is linked to chromosome replication in Escherichia coli

G Liu et al. Mol Microbiol. 2001 May.
Free article

Abstract

Cell division normally follows the completion of each round of chromosome replication in Escherichia coli. Transcription of the essential cell division genes clustered at the mra region is shown here to depend on continuing chromosomal DNA replication. After chromosome replication was blocked by either nalidixic acid treatment or thymine starvation, the transcription of these cell division genes was repressed significantly. This suggests a way in which cell division is controlled by chromosome replication.

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