Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001 Jul;69(7):4657-60.
doi: 10.1128/IAI.69.7.4657-4660.2001.

Variation in the infectivity of Listeria monocytogenes isolates following intragastric inoculation of mice

A H Barbour  1 , A Rampling, C E Hormaeche
Affiliations

Variation in the infectivity of Listeria monocytogenes isolates following intragastric inoculation of mice

A H Barbour et al. Infect Immun. 2001 Jul.

Abstract

The infectivities of 66 Listeria monocytogenes isolates were assessed by intragastric inoculation of mice. Eight were poorly infective. Serovars 4b and 1/2 were more infective than serovars 3 and 4nonb. A noninfective isolate was cleared more rapidly from the cecum than were infective isolates, suggesting that survival in the gut may relate to infectivity.

PubMed Disclaimer

Figures

FIG. 1
FIG. 1
Viable bacterial counts in spleen (a), liver (b), and cecal contents (c) of mice inoculated i.g. with 2 × 109 CFU of selected isolates of L. monocytogenes. Each point represents the mean of the log10s of the viable count per gram of tissue for three mice on days 1 to 4 and two mice on days 5 and 7.
FIG. 2
FIG. 2
Infectivities of 66 isolates of L. monocytogenes, grouped by serovar, assessed by viable bacterial counts in spleen (a) and liver (b) 3 days following i.g. inoculation with 2 × 109 CFU. Results are expressed as the means of the log10s of the viable counts per organ from three mice per isolate grouped in 1-log intervals.
FIG. 3
FIG. 3
The average (mean) infectivity of the different serovars of L. monocytogenes assessed by viable bacterial counts in spleen (a) and liver (b) 3 days following i.g. inoculation with 2 × 109 CFU. The graph shows the mean of results from each serovar expressed as log10 CFU per organ ± 95% confidence interval (error bars).
See this image and copyright information in PMC

References

    1. Audurier A, Pardon P, Marly J, Lantier F. Experimental infection of mice with Listeria monocytogenes and Listeria innocua. Ann Microbiol (Inst Pasteur) 1980;131B:47–57. - PubMed
    1. Barbour A H, Rampling A, Hormaeche C E. Comparison of the infectivity of isolates of Listeria monocytogenes following intragastric and intravenous inoculation in mice. Microb Pathog. 1996;20:247–253. - PubMed
    1. Bille J. Epidemiology of listeriosis in Europe with special reference to the Swiss outbreak. In: Miller A, Smith J L, Somkuti G A, editors. Foodborne listeriosis. New York, N.Y: Elsevier Science Publishers, Inc.; 1990. pp. 71–74.
    1. Conner D E, Scott V N, Sumner S S, Bernard D T. Pathogenicity of foodborne, environmental and clinical isolates of Listeria monocytogenes in mice. J Food Sci. 1989;54:1553–1556.
    1. Cossart P, Vicente M F, Mengaud J, Baquero F, Perez-Diaz J C, Berche P. Listeriolysin O is essential for virulence of Listeria monocytogenes: direct evidence obtained by gene complementation. Infect Immun. 1989;57:3629–3636. - PMC - PubMed

LinkOut - more resources