Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001 Jun;13(3):317-25.
doi: 10.1016/s0952-7915(00)00221-1.

Tec kinases: modulators of lymphocyte signaling and development

C M Lewis  1 , C Broussard, M J Czar, P L Schwartzberg
Affiliations
Review

Tec kinases: modulators of lymphocyte signaling and development

C M Lewis et al. Curr Opin Immunol. 2001 Jun.

Abstract

The Tec kinases are implicated as important components of the antigen receptor signaling required for proper lymphocyte activation and development. Recent data suggest that these kinases contribute to multiprotein complexes containing LAT and SLP-76 in T cells, and BLNK/SLP-65 in B cells, which are required for activation of PLC-gamma and downstream pathways.

PubMed Disclaimer

Publication types

Substances

LinkOut - more resources