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Review
. 2001 Jun;11(3):354-63.
doi: 10.1016/s0959-440x(00)00215-3.

Determination of protein function, evolution and interactions by structural genomics

S A Teichmann  1 , A G Murzin, C Chothia
Affiliations
Review

Determination of protein function, evolution and interactions by structural genomics

S A Teichmann et al. Curr Opin Struct Biol. 2001 Jun.

Abstract

The genome sequencing projects and knowledge of the entire protein repertoires of many organisms have prompted new procedures and techniques for the large-scale determination of protein structure, function and interactions. Recently, new work has been carried out on the determination of the function and evolutionary relationships of proteins by experimental structural genomics, and the discovery of protein-protein interactions by computational structural genomics.

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