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. 2001 Jul;45(7):2151-3.
doi: 10.1128/AAC.45.7.2151-2153.2001.

In vitro activities of four novel triazoles against Scedosporium spp

A J Carrillo  1 , J Guarro
Affiliations

In vitro activities of four novel triazoles against Scedosporium spp

A J Carrillo et al. Antimicrob Agents Chemother. 2001 Jul.

Abstract

In order to develop new approaches to the treatment of the severe and usually fatal infections caused by Scedosporium spp., the in vitro antifungal activities of four novel triazoles (posaconazole, ravuconazole, voriconazole, and UR-9825) and some current antifungals (amphotericin B, ketoconazole, itraconazole, and nystatin) were determined. The latter group was clearly ineffective against the two species tested. The four new antifungals showed activity against Scedosporium apiospermum, and UR-9825 and voriconazole were active against S. prolificans.

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