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Comment
. 2001 Jun;107(12):1501-2.
doi: 10.1172/JCI13318.

Pulmonary fibrosis: a cellular overreaction or a failure of communication?

D Sheppard  1
Affiliations
Comment

Pulmonary fibrosis: a cellular overreaction or a failure of communication?

D Sheppard. J Clin Invest. 2001 Jun.
No abstract available

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Figures

Figure 1
Figure 1
A few of the inductive and inhibitory signals involved in normal lung development. Some of the same signals are likely to be required for normal lung repair.
See this image and copyright information in PMC

Comment on

References

    1. Kuhn C, et al. An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis. Am Rev Respir Dis. 1989;140:1693–1703. - PubMed
    1. Selman M, King TE, Jr, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med. 2001;134:136–151. - PubMed
    1. Kolb M, Margetts PJ, Anthony DC, Pitossi F, Gauldie J. Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis. J Clin Invest. 2001;107:1529–1536. - PMC - PubMed
    1. Dinarello C. Biological basis for interleukin-1 in disease. Blood. 1996;87:2095–2147. - PubMed
    1. Jones AW, Reeve NL. Ultrastructural study of bleomycin-induced pulmonary changes in mice. J Pathol. 1978;124:227–233. - PubMed

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