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. 1975 Jun;28(6):498-501.
doi: 10.1136/jcp.28.6.498.

Effect of oral contraceptives on factor VIII clotting activity and factor VIII related antigen in normal women

P Stableforth, D C Montgomery, E Wilson, W G Churchill, K M Dormandy, R M Hardisty

Effect of oral contraceptives on factor VIII clotting activity and factor VIII related antigen in normal women

P Stableforth et al. J Clin Pathol. 1975 Jun.

Abstract

The factor VIII clotting activity (VIIIc1 and factor VIII related antigen (VIIIRAg) were determined repeatedly in 24 pairs of age-matched normal women, one of each pair being on oral contraceptives. No significant differences in either parameter or in the VIIIc/VIIIRAg ration were found between the two groups ,although the mean factor VIII clotting activity and VIIIc/VIIIRAg ratios for women on oral contraceptives were very slightly higher than for those not on oral contraceptives.

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