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Review
. 2001 Jun;3(7):549-59.
doi: 10.1016/s1286-4579(01)01411-3.

Salmonella pathogenicity islands encoding type III secretion systems

I Hansen-Wester  1 , M Hensel
Affiliations
Free article
Review

Salmonella pathogenicity islands encoding type III secretion systems

I Hansen-Wester et al. Microbes Infect. 2001 Jun.
Free article

Abstract

Salmonella enterica harbours two Salmonella pathogenicity islands (SPIs) each encoding a type III secretion system for virulence proteins. SPI1 is required for invasion, while systemic infections and intracellular accumulation of Salmonella are dependent on SPI2 function. This review will describe and compare the genetic organisation, evolution, regulation and molecular functions of SPI1 and SPI2.

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