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Case Reports
. 2001 Jun;20(6):623-7.
doi: 10.1097/00006454-200106000-00016.

Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials

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Case Reports

Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials

T Singhal et al. Pediatr Infect Dis J. 2001 Jun.

Abstract

Acanthamoeba was implicated as the causative agent of chronic meningitis in three apparently immunocompetent children. Diagnosis was established by cerebrospinal fluid wet mount examination and culture. Two children improved rapidly with combination oral therapy composed of trimethoprim-sulfamethoxazole, rifampin and ketoconazole.

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