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. 2001 Jul;39(7):2652-4.
doi: 10.1128/JCM.39.7.2652-2654.2001.

Resistance-associated mutations in the human immunodeficiency virus type 1 subtype c protease gene from treated and untreated patients in the United Kingdom

P A Cane  1 , A de Ruiter, P Rice, M Wiselka, R Fox, D Pillay
Affiliations

Resistance-associated mutations in the human immunodeficiency virus type 1 subtype c protease gene from treated and untreated patients in the United Kingdom

P A Cane et al. J Clin Microbiol. 2001 Jul.

Abstract

This work reports the variability of human immunodeficiency virus type 1 (HIV-1) protease from treated and untreated patients infected with HIV-1 subtype C in the United Kingdom. The most common primary mutation observed in treated patients was L90M. D30N, M46I, V82A/F, and I84V were seen rarely. M36I and I93L mutations were observed in nearly all samples from both treated and untreated patients and so cannot be considered as resistance-associated mutations in this subtype.

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