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. 2001 Feb 8;3(3):437-40.
doi: 10.1021/ol006942q.

Bogorol A produced in culture by a marine Bacillus sp. reveals a novel template for cationic peptide antibiotics

T Barsby  1 , M T Kelly, S M Gagné, R J Andersen
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Bogorol A produced in culture by a marine Bacillus sp. reveals a novel template for cationic peptide antibiotics

T Barsby et al. Org Lett. .

Abstract

[figure: see text] Bogorol A (1), a novel peptide antibiotic active against MRSA and VRE, has been isolated from cultures of a marine Bacillus sp. collected in Papua New Guinea. The structure of bogorol A was elucidated by a combination of spectroscopic analyses and chemical degradation. Bogorol A illustrates a new structural template for "cationic peptide antibiotics".

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