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Review
. 2001 Jun;30(3):641-2.
doi: 10.1016/s0896-6273(01)00330-0.

Metal chelator decreases Alzheimer beta-amyloid plaques

G K Gouras  1 , M F Beal
Affiliations
Free article
Review

Metal chelator decreases Alzheimer beta-amyloid plaques

G K Gouras et al. Neuron. 2001 Jun.
Free article

Abstract

Transgenic mice developing beta-amyloid (Abeta) plaques are advancing experimental treatment strategies for Alzheimer's disease. The metal chelator, clioquinol, is reported by Cherny et al. (2001) to reduce Abeta plaques, presumably by chelation of Abeta-associated zinc and copper. This and other recent Abeta-modulating treatment approaches are discussed.

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